Managing Organ Dysfunction in the ICU

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The Importance of Managing Fluid Overload in Acute Kidney Injury
Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018
Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT
John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Coming Soon

Understanding Hypercapnia in Critically Ill Patients: Using Extracorporeal CO2 Removal (ECCO2R) to Optimise Outcomes

Patient Case Studies

56-year-old man who underwent transsphenoidal surgery for craniopharyngioma 26 d ago presented gradual headache and cerebrospinal...

29-year-old Ethiopian male who presented to the emergency room of Tikur Anbessa specialized hospital with 4 days history...

17-year-old man living in a rural area used his smartphone to record an audible clicking sound emanating from his thorax...

73-year-old man was displaying symptoms of massive gastrointestinal (GI) bleed. Surgical actions were performed to control...

78-year-old man was found unconscious after sliding from a rock. His history included hypertension, atrial fibrillation and...

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In the News

Potential Harms of Chloroquine, Hydroxychloroquine, and Azithromycin for Treating COVID-19
Chloroquine, hydroxychloroquine, and azithromycin are being used to treat and prevent coronavirus disease 2019 (COVID-19) despite weak evidence for effectiveness, and physicians and patients should be aware of the drugs’ potentially serious adverse events, according to a review published in...
New Consensus Statement on Chest Imaging During the COVID-19 Pandemic
A multinational consensus statement from the Fleischner Society on the role of chest imaging in the management of patients with coronavirus disease 2019 (COVID-19) was jointly published today in the journals Radiology and Chest. The statement is endorsed by the Radiological Society of North...
SARS-CoV-2 Found in Sputum, Fecal Samples After Pharyngeal Specimens No Longer Positive
Clinicians from the Institute of Infectious Diseases at Beijing Ditan Hospital, Beijing, China, found that some patients had positive real-time polymerase chain reaction (RT-PCR) test results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the sputum or feces after the...
Individuals Taking Glucocorticoids at High Risk for COVID-19
Individuals taking glucocorticoids for conditions such as asthma, allergies, and arthritis on a routine basis may be unable to mount a normal stress response and are at high risk if they are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a an editorial...
Cardiovascular Implications of Fatal Outcomes of Patients With COVID-19
By Denise Baez Myocardial injury was significantly associated with fatal outcomes in patients with coronavirus disease 2019 (COVID-19), while the prognosis of patients with underlying cardiovascular disease (CVD) but without myocardial injury appears relatively favourable, according to a study...
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Conference Reports

AI-Enabled ECG Identifies Patients With Left Ventricular Systolic Dysfunction Presenting to the ER With Dyspnoea

By Eric Ramos

CHICAGO -- April 2, 2020 -- An artificial intelligence (AI)-enabled ECG algorithm accurately identifies left ventricular dysfunction (LVSD) in patients presenting to the emergency department with dyspnoea, outperforming N-terminal-prohormone BNP (NT-pro BNP), according to a...

Use of Sodium Nitrite Fails to Improve Survival in Patients Who Have Suffered Out-of-Hospital Cardiac Arrest

By Alex Morrisson

WEST PALM BEACH, Fla -- April 1, 2020 - Use of sodium nitrite during active resuscitation did not significantly improve survival to hospital admission or to discharge among patients who suffered out-of-hospital cardiac arrest, according to a study presented at the...

Cerebral Blood Flow Velocity Predicts Outcomes Following Subarachnoid Haemorrhage

By Nancy Melville

ORLANDO, Fla -- February 17, 2020 -- Elevations in cerebral blood flow velocity in the middle cerebral artery (MCA), as assessed with transcranial Doppler ultrasound, are associated with poor outcomes following subarachnoid haemorrhage, according to a study presented...

Certain Biomarkers Are Elevated During Syncope, May Aid Diagnosis

By Eric Ramos

BARCELONA, Spain -- January 28, 2020 -- Levels of certain circulating microRNAs and vasoactive amines are significantly higher in patients with syncope and can be used for early detection and diagnosis, according to a study presented here at The International Conference of...

Immediate MRI in Emergency Department Improves Diagnosis of Scaphoid Fractures

By Nancy Melville

CHICAGO -- December 2, 2019 -- The use of immediate magnetic resonance imaging (MRI) in the emergency department (ED) improves diagnostic accuracy in identifying scaphoid and other wrist fractures while reducing overall costs, according to a study presented here at the...

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Recently Published

Abstracts in Multiple Sclerosis

Journal of Emergency Medicine
Abdominal Distention and Emesis in a Term Neonate
Holly S Rose, Alexandra K Monroe, M Olivia Titus, Ian D Kane
Pediatric Emergency Care
Evaluation of the Pattern of Use of a Pediatric Emergency Department in Italy
Alfonso Stefano Vitello, Antonio Clavenna, Massimo Cartabia, Debora Sala, Andrea Biondi, Maurizio Bonati
Academic Emergency Medicine
Ketamine vs opioids for acute pain in the emergency department
Michael J Duhaime, Allan B Wolfson
Advances in Therapy
Service Evaluation of Methoxyflurane Versus Standard Care for Overall Management of Patients with Pain Due to Injury
Louise Young, George P Bailey, Jayne A C McKinlay
BMJ Case Reports
Blunt laryngeal trauma presenting as bilateral massive pneumothoraces and subcutaneous emphysema: a multidisciplinary approach to management
Christopher W Noel, Suneel Kumar Pooboni, Gamal Metwalli Metwalli, Safeena Kherani
See more >>

Full-Text Articles

Critical Care
Respiratory Muscle Rehabilitation in Patients with Prolonged Mechanical Ventilation: A Targeted Approach
Bernie Bissett, Rik Gosselink, Frank M P van Haren
BMJ Open
Cardiac arrest after pulmonary aspiration in hospitalised patients: a national observational study
Malin Albert, Johan Herlitz, Araz Rawshani, Mattias Ringh, Andreas Claesson, Therese Djärv, Per Nordberg
International Heart Journal
Poor Long-Term Survival of Out-of-Hospital Cardiac Arrest in Children
Satoshi Matsui, Tomotaka Sobue, Taro Irisawa, Tomoki Yamada, Koichi Hayakawa, Kazuhisa Yoshiya, Kazuo Noguchi, Tetsuro Nishimura, Takuya Ishibe, Yoshiki Yagi, Takeyuki Kiguchi, Masafumi Kishimoto, Hiroshi Shintani, Yasuyuki Hayashi, Taku Sogabe, Takaya Morooka, Haruko Sakamoto, Keitaro Suzuki, Fumiko Nakamura, Norihiro Nishioka, Yohei Okada, Tasuku Matsuyama, Junya Sado, Takeshi Shimazu, Ryojiro Tanaka, Hiroshi Kurosawa, Taku Iwami, Tetsuhisa Kitamura, CRITICAL Study Group Investigators
Journal of the American College of Cardiology (JACC)
Early Diagnosis of Myocardial Infarction With Point-of-Care High-Sensitivity Cardiac Troponin I
Jasper Boeddinghaus, Thomas Nestelberger, Luca Koechlin, Desiree Wussler, Pedro Lopez-Ayala, Joan Elias Walter, Valentina Troester, Paul David Ratmann, Funda Seidel, Tobias Zimmermann, Patrick Badertscher, Karin Wildi, Maria Rubini Giménez, Eliska Potlukova, Ivo Strebel, Michael Freese, Òscar Miró, F Javier Martin-Sanchez, Damian Kawecki, Dagmar I Keller, Danielle M Gualandro, Michael Christ, Raphael Twerenbold, Christian Mueller, APACE Investigators
Journal of the American Heart Association
Mechanical, Team-Focused, Video-Reviewed Cardiopulmonary Resuscitation Improves Return of Spontaneous Circulation After Emergency Department Implementation
Daniel M Rolston, Timmy Li, Casey Owens, Ghania Haddad, Timothy J Palmieri, Veronika Blinder, Jennifer L Wolff, Michael Cassara, Qiuping Zhou, Lance B Becker
See more >>

PeerVoice invites you to explore the education and resources on this site that provides a comprehensive approach to managing your patients.

User-friendly learning modules available in short and accessible formats.


Insights and developments from leading experts.


Continuously updated news and conference coverage.


Helpful resources for your practice and patients.


Resource Library

CRRT Online: Acute Therapy Resources

Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group

Nadim MK et al. J Am Heart Assoc. 2018;7:e008834

KDIGO Clinical Practice Guideline for Acute Kidney Injury

Kidney Int Suppl. 2012;2:1-128

Fluid Management for the Prevention and Attenuation of Acute Kidney Injury

Prowle JR et al. Nat Rev Nephrol. 2014;10:37-47

Fluid Management in Acute Kidney Injury

Goldstein SL. J Intensive Care Med. 2014;29:183-189

Indications and Management of Mechanical Fluid Removal in Critical Illness

Rosner MH et al. Br J Anaesth. 2014;113:764-771

Recovery After Acute Kidney Injury

Kellum JA et al. Am J Respir Crit Care Med. 2017;195:784-791

Prevention of Cardiac Surgery–Associated AKI by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI Randomised Controlled Trial

Meersch M et al. Intensive Care Med. 2017;43:1551-1561

Effect of Remote Ischaemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery: A Randomised Clinical Trial

Zarbock A et al. JAMA. 2015;313:2133-2141

Strategies for the Optimal Timing to Start Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury

Bagshaw SM, Wald R. Kidney Int. 2017;91:1022-1032

Early vs Late Initiation of Renal Replacement Therapy Impacts Mortality in Patients With Acute Kidney Injury Post-Cardiac Surgery: A Meta-Analysis

Zou H et al. Crit Care. 2017;21:150