Managing Organ Dysfunction in the ICU

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Hypercapnia in the Intensive Care Unit: What Do I Need to Know?

Eddy Fan, MD, PhD
8 March 2021

The Role of Extracorporeal Carbon Dioxide Removal (ECCO₂R) in Patients With Acute Respiratory Distress Syndrome (ARDS)

Alain Combes, MD, PhD
8 March 2021

Predicting Risk of Persistent Severe Acute Kidney Injury: The Role of CCL14

John A. Kellum, MD, MCCM
11 November 2020

Exploring the Implications of Early Biomarkers for Persistent Severe AKI

Claudio Ronco, MD
11 November 2020

Acute Kidney Injury: A Significant Complication After Cardiac Surgery

John A. Kellum Jr., MD, MCCM
15 March 2019

Best Practices and Preferred Approaches to Managing CSA-AKI in the ICU

Alexander Zarbock, MD
15 March 2019

The Importance of Managing Fluid Overload in Acute Kidney Injury

Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018

Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT

John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Patient Case Studies

60-year-old male with a history of severe depression presented to the emergency department after intentional ingestion of...

57-year-old man presented to the emergency department 9 days after developing testicular pain while lifting his lawnmower...

20-year-old woman presenting to the emergency department (ED) with unilateral leg swelling. After multiple visits to the...

29-year-old woman who was brought by family members to our Emergency Department (ED) in Riyadh, Saudi Arabia with sudden...

36-year-old gravida 2 para 1 woman at 38 weeks of gestation. A caesarean section was performed for severe pre-eclampsia,...

In the News

Early Warning System for Sepsis Improves Survival Rates, Reduces Hospital Stays

Patients who presented to the emergency departments and were flagged by an artificial intelligence (AI) algorithm for possibly having sepsis received antibiotics sooner and had better outcomes, according to a study published in Critical Care Medicine. “We showed that when providers had access to...

Initial Treatment of MIS-C With IVIG and Glucocorticoids Reduces Risk of Cardiovascular Dysfunction

Treating multisystem inflammatory syndrome in children (MIS-C) initially with intravenous immune globulin (IVIG) and glucocorticoids reduced the risk of serious short-term adverse outcomes, including cardiovascular dysfunction, than those who receive an initial treatment of IVIG alone, according to...

Myocarditis in Younger Men Following COVID-19 Vaccination Not Common, But Higher Than Expected

By Denise Baez Myocarditis occurred in previously healthy military patients with similar clinical presentations following receipt of an mRNA coronavirus disease 2019 (COVID-19) vaccine, according to a study published in JAMA Cardiology. “In this case series, we describe 23 patients with clinical...

Magnets in Cell Phones and Smart Watches May Affect Pacemakers, Other Implanted Medical Devices

Some consumer electronic devices with high field strength magnets, such as cell phones and smart watches, may cause certain implanted medical devices to switch to “magnet mode” and suspend normal operations until the magnet is moved away from the medical device. Many implanted medical devices are...

ACP Recommends Use of Point-of-Care Ultrasonography to Improve Diagnosis of Patients With Acute Dyspnoea

By Denise Baez The American College of Physicians (ACP) has published new guidelines recommending point-of-care ultrasonography (POCUS), in addition to the standard diagnostic pathway, when there is diagnostic uncertainty in patients with acute dyspnoea in emergency department or inpatient...

Conference Reports

Clinical Frailty Is Associated With Increased In-Hospital, Mortality in Patients With COVID-19

By Nancy Melville

BRUSSELS -- September 7, 2021 -- Patients with coronavirus disease 2019 (COVID-19) who have high scores indicating clinical frailty show significantly higher rates of in-hospital and 30-day mortality, according to a study presented at the 40th International Symposium on...

Intravenous Immunoglobulins Decrease the Incidence of Bacterial Secondary Infections in Patients With Severe COVID-19

By Nancy Melville

BRUSSELS -- September 7, 2021 -- The addition of intravenous (IV) immunoglobulin therapy to antibiotics significantly prevented secondary infections and mortality among patients with severe coronavirus disease 2019 (COVID-19) who required mechanical ventilation,...

Peritoneal Fluid Sampling During Emergency Laparotomy Influences Subsequent Antimicrobial Prescriptions in the ICU

By Nancy Melville

BRUSSELS -- September 7, 2021 -- The sampling of peritoneal fluid during emergency laparotomy influences subsequent antimicrobial prescriptions in the intensive care unit (ICU), according to a study presented at the 40th International Symposium on Intensive Care and...

Timing of Dynamic Monitoring in Sepsis Fluid Resuscitation Affects Outcomes

By Nancy Melville

BRUSSELS -- September 3, 2021 -- Patients with septic shock who have dynamic measurement of stroke volume following a fluid challenge in the first two days show significantly greater improvements in outcomes and a lower risk of death compared with those receiving...

Over-Sedation in Patients With COVID-19, ARDS, Linked to Delirium Risk

By Nancy Melville

BRUSSELS -- September 3, 2021 -- Critically-ill patients with coronavirus disease 2019 (COVID-19) and/or acute respiratory distress syndrome (ARDS) who are over-sedated are at an increased risk of delirium, regardless of their age, according to a study presented at the...

Recently Published

Abstracts in Multiple Sclerosis

Journal of Thrombosis and Thrombolysis

COVID-19 risk index (CRI): a simple and validated emergency department risk score that predicts mortality and the need for mechanical ventilation

Mohamad Raad, Sarah Gorgis, Chelsea Abshire, Monica Yost, Mohammed F Dabbagh, Omar Chehab, Lindsey Aurora, Sati Patel, Paul Nona, Jerry Yan, Gurjit Singh, John Syrjamaki, Scott Kaatz, Sachin Parikh

Journal of Emergency Medicine

A Case of Psoas Muscle Abscess With Hematuria, Detected Initially by Point-of-Care Ultrasound in the Emergency Department

Yu-Nong Lai, Jui-Yuan Chung

Journal of Intensive Care Medicine

Transesophageal Echocardiography Performed by Intensivist and Emergency Physicians-A 5-Year, Single-Center Experience

Trenton C Wray, Molly Johnson, Shelby Cluff, Fiona T Nguyen, Isaac Tawil, Darren Braude, Wendy Hanna, Keith Azevedo, Ranjani Venkataramani, Todd S Dettmer, Jonathan Marinaro

Skeletal Radiology

The use of cone-beam computed tomography (CBCT) in radiocarpal fractures: a diagnostic test accuracy meta-analysis

Emma Fitzpatrick, Vivek Sharma, Djamila Rojoa, Firas Raheman, Harvinder Singh

BMJ Case Reports

Cardiac tamponade and massive pleural effusion in a young COVID-19-positive adult

Dilip Johny, Kodangala Subramanyam, Nandakishore Baikunje, Giridhar Belur Hosmane

Full-Text Articles

BMJ Open

Comparing lung ultrasound: extensive versus short in COVID-19 (CLUES): a multicentre, observational study at the emergency department

Bram Kok, Frederik Schuit, Arthur Lieveld, Kaoutar Azijli, Prabath Wb Nanayakkara, Frank Bosch

BMJ Open

COVID outcome prediction in the emergency department (COPE): using retrospective Dutch hospital data to develop simple and valid models for predicting mortality and need for intensive care unit admission in patients who present at the emergency department

David van Klaveren, Alexandros Rekkas, Jelmer Alsma, Rob J C G Verdonschot, Dick T J J Koning, Marlijn J A Kamps, Tom Dormans, Robert Stassen, Sebastiaan Weijer, Klaas-Sierk Arnold, Benjamin Tomlow, Hilde R H de Geus, Rozemarijn L van Bruchem-Visser, Jelle R Miedema, Annelies Verbon, Els van Nood, David M Kent, Stephanie C E Schuit, Hester Lingsma

International Journal of Infectious Diseases

Reactions and COVID-19 disease progression following SARS-CoV-2 monoclonal antibody infusion

Laurel Goldin, Ty Elders, Leslie Werhane, Kimberly Korwek, Russell Poland, Jeffrey Guy

Cerebrovascular Diseases

Extensive Cerebral Venous Thrombosis Secondary to Recreational Nitrous Oxide Abuse

Wassim Farhat, Aaron Pariente, Rami Mijahed

Internal medicine (Tokyo; Japan)

Persistent Hypoglycemia Induced by Long-acting Insulin Degludec

Yukino Katakura, Fuminori Tatsumi, Takashi Kusano, Masashi Shimoda, Kenji Kohara, Tomohiko Kimura, Atsushi Obata, Shuhei Nakanishi, Tomoatsu Mune, Kohei Kaku, Hideaki Kaneto