Managing Organ Dysfunction in the ICU

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The Importance of Managing Fluid Overload in Acute Kidney Injury
Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018
Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT
John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Coming Soon

Understanding Hypercapnia in Critically Ill Patients: Using Extracorporeal CO2 Removal (ECCO2R) to Optimise Outcomes

Patient Case Studies

9-year-old boy presented with his brother after they accidentally ingested a small amount of undiluted 22.4% sodium chlorite...

51-year-old woman with a 30-year history of a macroprolactinoma who was lost to follow-up and returned with severe proptosis,...

76-year-old man arriving to the emergency department (ED) with symptoms of fatigue and dysphagia, diagnosed as acute myasthenia...

59-year-old female admitted to the emergency department with intermittent left flank pain radiating to the left abdomen after...

40-year-old man presented to the emergency department after an in-vehicle traffic accident. He had no active complaint other...

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In the News

Hypokalaemia Is Associated With COVID-19 Severity, Need for Invasive Mechanical Ventilation
By Denise Baez NEW YORK - September 18, 2020 -- There is a high prevalence of hypokalaemia among patients with coronavirus disease 2019 (COVID-19) pneumonia, and is associated with disease severity and the need for invasive mechanical ventilation, according to a study published in the...
SARS-CoV-2 Viral Load Predicts Mortality in Hospitalised With COVID-19 With, Without Cancer
By Denise Baez NEW YORK -- September 17, 2020 -- High admission severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load predicts mortality in hospitalised patients with and without cancer, according to a study published in Cancer Cell. Lars F. Westblade, MD, Weill Cornell Medicine...
Azithromycin May Increase Risk of Cardiac Events Among Patients Using QT-Prolonging Drugs
A study published in JAMA Network Open found no association of cardiac events with azithromycin compared with amoxicillin, except among patients using other QT-prolonging drugs concurrently. “Although azithromycin is a safe therapy, clinicians should carefully consider its use among patients...
4C Mortality Score Predicts Risk of Death in Hospitalised Patients With COVID-19
By Denise Baez NEW YORK -- September 15, 2020 -- An easy-to-use risk stratification score, dubbed the 4C (Coronavirus Clinical Characterisation Consortium) Mortality Score, can be used to accurately categorise patients hospitalised with coronavirus disease 2019 (COVID-19) as being at low,...
New IDSA Guidelines on Optimal Use of SARS-CoV-2 Serologic Testing in a Variety of Settings
By Denise Baez NEW YORK -- September 15, 2020 -- The Infectious Diseases Society of America (IDSA) has published evidence-based recommendations to assist clinicians, clinical laboratories, patients, and policymakers in decisions related to the optimal use of severe acute respiratory syndrome...
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Conference Reports

Randomised Study Confirms Patients With COVID-19, Hypertension Can Continue ACEI/ARB Treatment

By Eric Ramos

CHICAGO -- September 7, 2020 -- Patients with hypertension who are hospitalised due to mild or moderate coronavirus disease 2019 (COVID-19) can continue to safely take angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) while being...

Which Patients With Acute Pulmonary Embolism Can Be Managed at Home?

By Eric Ramos

CHICAGO -- September 7, 2020 -- Outpatient care of normotensive patients with acute pulmonary embolism (PE) is feasible, according to a study presented at the Virtual 2020 European Society of Cardiology (ESC) Congress.

Results from the HOME-PE study showed that using...

Ambulatory Management of Spontaneous Pneumothorax Reduces Hospital Stay

By Nancy Melville

YORK, Me -- August 11, 2020 -- Patients with primary spontaneous pneumothorax treated with ambulatory decompression management show significantly improved outcomes and reduced hospitalisation, although adverse events may be higher than standard care, according to a study...

Trocar Technique Shows Fewer Complications Than Seldinger for Cholecystostomy

By Nancy Melville

YORK, Me -- July 24, 2020 -- The bedside, ultrasound-guided Trocar technique for percutaneous cholecystostomy shows efficacy that is similar to the ultrasound- and fluoroscopy-guided Seldinger technique, with benefits including fewer complications requiring less time,...

Algorithm Can Identify Patients With COVID-19 Who May Benefit From Hydroxychloroquine

CEPAGATTI, Italy -- July 19, 2020 -- Use of a machine-learning algorithm can identify patients with coronavirus disease 2019 (COVID-19) who would benefit from treatment with hydroxychloroquine, according to a study presented at the Virtual Congress of the International Society on Thrombosis and...

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Recently Published

Abstracts in Multiple Sclerosis

Journal of Pediatric Orthopaedics Part B
One-year prospective analysis of hand and forearm injuries in children
Murat Celal Sozbilen, Ali Engin Dastan, Huseyin Gunay, Levent Kucuk
Pain Medicine
Brief Pain Inventory-Short Form: A New Method for Assessing Pain in the Emergency Department
Dana D Im, Guruprasad D Jambaulikar, Anna Kikut, Jasmine Gale, Scott G Weiner
BMJ Case Reports
Survival case of acute and severe respiratory distress due to spontaneous tension gastrothorax
Sanjan Asanaru Kunju, Prithvishree Ravindra, Ramya Kumar Madabushi Vijay, Priya Pattath Sankaran
BMJ Case Reports
Angioedema, ACE inhibitor and COVID-19
Ekjot Grewal, Bayu Sutarjono, Ibbad Mohammed
BMJ Case Reports
Near-fatal negative pressure pulmonary oedema successfully treated with venovenous extracorporeal membrane oxygenation performed in the hybrid emergency room
Kazuki Matsumura, Yukitoshi Toyoda, Shokei Matsumoto, Tomohiro Funabiki
See more >>

Full-Text Articles

Journal of Cardiothoracic Surgery
New acute respiratory management in tracheal rupture caused by chest trauma
Cheng Shen, Lin Ma
Trials
Non-steroidal or opioid analgesia use for children with musculoskeletal injuries (the No OUCH study): statistical analysis plan
Anna Heath, Maryna Yaskina, Gareth Hopkin, Terry P Klassen, Christopher McCabe, Martin Offringa, Petros Pechlivanoglou, Juan David Rios, Naveen Poonai, Samina Ali, KidsCAN PERC Innovative Pediatric Clinical Trials No OUCH Study Group
Intensive Care Medicine
Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia
Laurent Zieleskiewicz, Thibaut Markarian, Alexandre Lopez, Chloé Taguet, Neyla Mohammedi, Mohamed Boucekine, Karine Baumstarck, Guillaume Besch, Gautier Mathon, Gary Duclos, Lionel Bouvet, Pierre Michelet, Bernard Allaouchiche, Kathia Chaumoître, Mathieu Di Bisceglie, Marc Leone, AZUREA Network
Clinics and Research in Hepatology and Gastroenterology
Uncommon presentation of COVID-19: Gastrointestinal bleeding
Muge Gulen, Salim Satar
World Neurosurgery
Glass Fragment Injury to the Craniocervical Junction with Interatlantooccipital Penetration to the Subarachnoid Space: Not-To-Be-Missed Important Aspects of Craniocervical Trauma Even in the Middle of the COVID-19 Pandemic: Case Report and Review of Liter
Yuichiro Yoneoka, Katsuhiko Akiyama, Yasuhiro Seki
See more >>

PeerVoice invites you to explore the education and resources on this site that provides a comprehensive approach to managing your patients.

User-friendly learning modules available in short and accessible formats.


Insights and developments from leading experts.


Continuously updated news and conference coverage.


Helpful resources for your practice and patients.


Resource Library

CRRT Online: Acute Therapy Resources

Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group

Nadim MK et al. J Am Heart Assoc. 2018;7:e008834

KDIGO Clinical Practice Guideline for Acute Kidney Injury

Kidney Int Suppl. 2012;2:1-128

Fluid Management for the Prevention and Attenuation of Acute Kidney Injury

Prowle JR et al. Nat Rev Nephrol. 2014;10:37-47

Fluid Management in Acute Kidney Injury

Goldstein SL. J Intensive Care Med. 2014;29:183-189

Indications and Management of Mechanical Fluid Removal in Critical Illness

Rosner MH et al. Br J Anaesth. 2014;113:764-771

Recovery After Acute Kidney Injury

Kellum JA et al. Am J Respir Crit Care Med. 2017;195:784-791

Prevention of Cardiac Surgery–Associated AKI by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI Randomised Controlled Trial

Meersch M et al. Intensive Care Med. 2017;43:1551-1561

Effect of Remote Ischaemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery: A Randomised Clinical Trial

Zarbock A et al. JAMA. 2015;313:2133-2141

Strategies for the Optimal Timing to Start Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury

Bagshaw SM, Wald R. Kidney Int. 2017;91:1022-1032

Early vs Late Initiation of Renal Replacement Therapy Impacts Mortality in Patients With Acute Kidney Injury Post-Cardiac Surgery: A Meta-Analysis

Zou H et al. Crit Care. 2017;21:150