Managing Organ Dysfunction in the ICU

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Hypercapnia in the Intensive Care Unit: What Do I Need to Know?

Eddy Fan, MD, PhD
8 March 2021

The Role of Extracorporeal Carbon Dioxide Removal (ECCO₂R) in Patients With Acute Respiratory Distress Syndrome (ARDS)

Alain Combes, MD, PhD
8 March 2021

Predicting Risk of Persistent Severe Acute Kidney Injury: The Role of CCL14

John A. Kellum, MD, MCCM
11 November 2020

Exploring the Implications of Early Biomarkers for Persistent Severe AKI

Claudio Ronco, MD
11 November 2020

Acute Kidney Injury: A Significant Complication After Cardiac Surgery

John A. Kellum Jr., MD, MCCM
15 March 2019

Best Practices and Preferred Approaches to Managing CSA-AKI in the ICU

Alexander Zarbock, MD
15 March 2019

The Importance of Managing Fluid Overload in Acute Kidney Injury

Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018

Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT

John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Patient Case Studies

51-year-old female with prior history of ventriculoperitoneal shunt presented with worsening abdominal distension. Her abdomen...

57-year-old male patient who developed SCC damage after GLA poisoning. The patient had various late-onset neurotoxic symptoms,...

33-year-old male with a history of anabolic steroid use and bovine thyroid hormone use presented to the emergency department...

45-year-old Chinese woman was admitted to the hospital to address a complaint of intermittent shortness of breath, which...

56-year-old male presented with atraumatic left knee pain and swelling. Radiographically, he had tricompartmental osteoarthritis...

In the News

ACP Recommends Use of Point-of-Care Ultrasonography to Improve Diagnosis of Patients With Acute Dyspnoea

By Denise Baez The American College of Physicians (ACP) has published new guidelines recommending point-of-care ultrasonography (POCUS), in addition to the standard diagnostic pathway, when there is diagnostic uncertainty in patients with acute dyspnoea in emergency department or inpatient...

FDA Approves Higher Dosage of Naloxone Nasal Spray to Treat Opioid Overdose

The US Food and Drug Administration (FDA) has approved a higher dose of naloxone hydrochloride nasal spray to treat opioid overdose. The newly approved product delivers naloxone 8 mg into the nasal cavity. The FDA had previously approved naloxone 2 mg and 4 mg nasal spray products. “Today’s action...

AHA/ASA Publish Guidance on Treatment for Vaccine-Induced Immune Thrombotic Thrombocytopenia

The American Heart Association/American Stroke Association (AHA/ASA) Stroke Council Leadership convened quickly to provide important guidance about cerebral venous sinus thrombosis (CVST) and thrombocytopenia, together called thrombosis and thrombocytopenia syndrome (TTS), in patients who have...

New Machine Learning-Based Tool to Help Physicians Determine Best Test for Chest Pain

By applying machine learning techniques to data from 2 large clinical trials, researchers have created a new digital decision-aiding tool, called ASSIST, that can identify which imaging test to pursue in patients who may have coronary artery disease (CAD). The new tool, described in a study...

CDC’s ACIP: Benefits of Janssen Vaccine Outweigh the Risks, Pause Lifted

By Denise Baez The Centers for Disease Control and Prevention’s (CDC’s) Advisory Committee on Immunization Practices (ACIP) recommended that the Janssen/J...

Conference Reports

Early Use of Mechanical Circulatory Support, Invasive Haemodynamics Improve Outcomes for Patients in Cardiogenic Shock

By Eric Ramos

VIRTUAL -- April 29, 2021 -- Early use of mechanical circulatory support and invasive haemodynamics are associated with improved outcomes for patients presenting with acute myocardial infarction (MI) and cardiogenic shock, according to final results from the National...

Elevated BP Variability During Transport for Endovascular Thrombectomy Is Associated With Worse Functional Outcome

By Erika Powers

VIRTUAL -- April 27, 2021 -- Elevated pre-procedural blood pressure variability during interhospital transport for endovascular thrombectomy is associated with lower odds of good functional outcome at 90 days, according to a study presented at the Virtual 2021 Annual...

Splenic Artery Embolization for Blunt Spleen Injuries Associated With Decreased Mortality, Length of Stay vs Splenectomy

By Erika Powers

CLEVELAND, Ohio -- March 29, 2021 -- Compared with splenectomy, treatment of blunt spleen injuries with splenic artery embolization was associated with decreased mortality and length of stay, without an increase in abscess formation, according to a study presented at the...

Stroke Treatment in Critical “Golden Hour” More Likely in Mobile Stroke Units

By Nancy Melville

YORK, Me -- March 24, 2021 -- Patients who receive stroke treatment in a mobile stroke unit are significantly more likely to receive potentially life-saving clot-buster treatment, to receive treatment within 1 hour of stroke onset, and to achieve a full recovery than...

Specific CT Findings Can Help in Diagnosis of Perforated Versus Non-Perforated Acute Appendicitis

By Erika Powers

CLEVELAND, Ohio -- March 10, 2021 -- Certain preoperative CT findings can be helpful in predicting appendiceal perforation, according to a study presented at the Virtual 2021 European Congress of Radiology (ECR).

“Acute appendicitis is the most common cause for...

Recently Published

Abstracts in Multiple Sclerosis

Emergency Medicine Journal

Experience of emergency department patients after a visit for hyperglycaemia: implications for communication and factors affecting adherence postdischarge

Justin Yan, Dimah Azzam, Melanie Columbus, Kristine Van Aarsen, Selina Liu, Tamara Spaic, Lisa Shepherd, Network of Canadian Emergency Researchers

Clinical Medicine

Acute neurological consequences of novel psychoactive substance use: a retrospective review in a large UK hospital

Matthew Tanti, Jeremy Cosgrove, Charles Kelleher, Rebekah Jones, Melissa Maguire

Radiologia

Urgent ultrasound-guided interventional procedures

G Arenaza Choperena, V Gómez Usabiaga, A Ugarte Nuño, G Gabilondo Rikondo

Emergency Medicine Australasia

Bacterial infection secondary to Trimeresurus species bites: A retrospective cohort study in a university hospital in Bangkok

Suppanut Kriengkrairut, Rittirak Othong

Internal and Emergency Medicine

Characteristic of IgA and IgG antibody response to SARS-CoV-2 infection in an Italian referral COVID-19 Hospital

Annamaria Carnicelli, Barbara Fiori, Rosalba Ricci, Alfonso Piano, Nicola Bonadia, Eleonora Taddei, Massimo Fantoni, Rita Murri, Antonella Cingolani, Christian Barillaro, Salvatore Lucio Cutuli, Debora Marchesini, Davide Antonio Della Polla, Evelina Forte, Mariella Fuorlo, Luca Di Maurizio, Paola Amorini, Paola Cattani, Francesco Franceschi, Maurizio Sanguinetti

Full-Text Articles

BMJ Open

Performance of seven different paediatric early warning scores to predict critical care admission in febrile children presenting to the emergency department: a retrospective cohort study

Sam T Romaine, Gerri Sefton, Emma Lim, Ruud G Nijman, Jolanta Bernatoniene, Simon Clark, Luregn J Schlapbach, Philip Pallmann, Enitan D Carrol

European Journal of Endocrinology

Treatment of symptomatic hyponatremia with hypertonic saline: a real-life observational study

Irina Chifu, Amelie Gerstl, Björn Lengenfelder, Dominik Schmitt, Nils Nagler, Martin Fassnacht, Dirk Weismann

Medicine (Baltimore)

Early blood pH as an independent predictor of neurological outcome in patients with out-of-hospital cardiac arrest: A retrospective observational study

Chin-Han Lin, Shao-Hua Yu, Chih-Yu Chen, Fen-Wei Huang, Wei-Kung Chen, Hong-Mo Shih

Scientific Reports

Development and validation of an early warning tool for sepsis and decompensation in children during emergency department triage

Louis Ehwerhemuepha, Theodore Heyming, Rachel Marano, Mary Jane Piroutek, Antonio C Arrieta, Kent Lee, Jennifer Hayes, James Cappon, Kamila Hoenk, William Feaster

Emergency Medicine Journal

Non-invasive assessment of fluid responsiveness to guide fluid therapy in patients with sepsis in the emergency department: a prospective cohort study

Nienke K Koopmans, Renate Stolmeijer, Ben C Sijtsma, Paul A van Beest, Christiaan E Boerma, Nic J Veeger, Ewoud Ter Avest