Managing Organ Dysfunction in the ICU

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The Importance of Managing Fluid Overload in Acute Kidney Injury
Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018
Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT
John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Patient Case Studies

74-year-old female patient with severe COVID-19 which progressed to ARDS requiring intubation and mechanical ventilation...

55-year-old female with a history of multiple allergic reactions who presented with respiratory distress and hives after...

58-year-old male, heavy smoker and with known SARS-CoV-2 infection, abruptly developed severe hypotension and asthenia. At...

38-year-old Japanese man with a mood disorder presented to our hospital with fever and diarrhea. Chest computed tomography...

47-year-old male patient diagnosed with MINOCA who was followed up with respiratory failure due to COVID-19 viral pneumonia...

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In the News

FDA Launches Public Adverse Event Monitoring Dashboard for COVID-19 EUA Products
The US Food and Drug Administration (FDA) has launched an adverse event reporting system dashboard, available to the public, for coronavirus disease 2019 (COVID-19) products that have been issued emergency use authorisation (EUA) by the FDA. The interactive web-based tool will allow for the...
Machine Learning Algorithm Uses EHR Data to Calculate Suicide Attempt Risk
Using information found in electronic health records (EHRs), researchers have created a real-time predictive model of suicide attempt risk which can be used to screen in non-psychiatric specialty settings. “We cannot screen every patient for suicide risk in every encounter -- nor should we,” said...
Study Finds Lower Dose of Ketamine Equally Effective in Reducing Pain
Reducing the standard dose of IV-administered ketamine in half is as effective as the larger, standard dose in reducing pain in adults with acute pain, according to a study published in the journal Academic Emergency Medicine. Ketamine is known to provide pain relief comparable to opioid...
SARS-CoV-2 Variant B.1.1.7 Associated With a Significantly Higher Mortality Rate
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern 202012/01 (VOC 202012/01), from lineage B.1.1.7, is between 30% and 100% more deadly than previous strains, according to a study published the British Medical Journal. Leon Danon, MD, University of Bristol, Bristol...
AHA: Central Retinal Artery Occlusion Requires Immediate Treatment, Can Signal Future Vascular Events
A new scientific statement from the American Heart Association, published in the journal Stroke, states that central retinal artery occlusion (CRAO) is a medical emergency and systems of care should evolve to prioritise early recognition and triage of CRAO to emergency medical attention. The...
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Conference Reports

Splenic Artery Embolization for Blunt Spleen Injuries Associated With Decreased Mortality, Length of Stay vs Splenectomy

By Erika Powers

CLEVELAND, Ohio -- March 29, 2021 -- Compared with splenectomy, treatment of blunt spleen injuries with splenic artery embolization was associated with decreased mortality and length of stay, without an increase in abscess formation, according to a study presented at the...

Stroke Treatment in Critical “Golden Hour” More Likely in Mobile Stroke Units

By Nancy Melville

YORK, Me -- March 24, 2021 -- Patients who receive stroke treatment in a mobile stroke unit are significantly more likely to receive potentially life-saving clot-buster treatment, to receive treatment within 1 hour of stroke onset, and to achieve a full recovery than...

Specific CT Findings Can Help in Diagnosis of Perforated Versus Non-Perforated Acute Appendicitis

By Erika Powers

CLEVELAND, Ohio -- March 10, 2021 -- Certain preoperative CT findings can be helpful in predicting appendiceal perforation, according to a study presented at the Virtual 2021 European Congress of Radiology (ECR).

“Acute appendicitis is the most common cause for...

Rothman Index at Time of Admission Identifies Patients With COVID-19 Susceptible to Rapid Deterioration

By Eric Ramos

CHICAGO -- February 1, 2021 -- Using the Rothman Index (RI) acuity score at the time of admission can identify patients with coronavirus disease 2019 (COVID-19) who are susceptible to rapid deterioration, according to a study presented at the Virtual 50th Annual Meeting of...

Sickle Cell Disease Confers Higher COVID-19 Mortality, Hospitalisation Risk

By Walter Alexander

NEW YORK -- December 8, 2020 -- Compared with the general black population in California, black patients with sickle cell disease who became infected with coronavirus disease 2019 (COVID-19) have higher rates of COVID-19 death, according to a study presented at the...

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Recently Published

Abstracts in Multiple Sclerosis

JAMA Internal Medicine
Association of Intravenous Radiocontrast With Kidney Function: A Regression Discontinuity Analysis
Robert Goulden, Brian H Rowe, Michal Abrahamowicz, Erin Strumpf, Robyn Tamblyn
International Journal of Clinical Practice
Lactate clearance during the first 2 hours after hospital admission: A useful biomarker for predicting 30-day mortality in patients with diabetic ketoacidosis
Abdullah İbrahim, Burcu Bayramoglu, Nihat Mujdat Hokenek, Davut Tekyol
Internal and Emergency Medicine
Elevation of the D-dimer cut-off level might be applicable to rule out pulmonary embolism for active cancer patients in the emergency department
Hyojeong Kwon, Youn-Jung Kim, Eun-Ju Her, Bora Chae, Yoon-Seon Lee
Internal Medicine Journal
Rhabdomyolysis-associated acute kidney injury: clinical characteristics and intensive care unit transfer analysis
De-Cai Zhu, Wen-Yan Li, Jia-Wen Zhang, Jun-Sheng Tong, Wen-Yuan Xie, Xiao-Lan Qin, Xiao-Chun Zhang
Obesity Surgery
Long-term Emergency Department Visits and Readmissions After Laparoscopic Roux-en-Y Gastric Bypass: a Systematic Review
N van Olst, A S van Rijswijk, S Mikdad, L J Schoonmade, A W van de Laar, Y I Z Acherman, S C Bruin, D L van der Peet, L M de Brauw
See more >>

Full-Text Articles

BMC Infectious Diseases
Independent predictors for 90-day readmission of emergency department patients admitted with sepsis: a prospective cohort study
Peer Oscar Overgaard Stenholt, S M Osama Bin Abdullah, Rune Husås Sørensen, Finn Erland Nielsen
BMJ Open
Which parameters support disposition decision in suspected COVID-19 cases in the emergency department (ED): a German clinical cohort study
Martin Möckel, Miriam Songa Stegemann, Volker Burst, Philipp Kümpers, Joachim Risse, Felix Carlo Koehler, Domagoj Schunk, Jennifer Hitzek, Tamara Elene Dietrich, Anna Slagman
Internal medicine (Tokyo; Japan)
Severe Anaphylactic Shock Following a Slow Loris Bite in a Patient with Cat Allergy
Fumiya Inoue, Akihiko Inoue, Takafumi Tsuboi, Tetsuya Ichikawa, Masafumi Suga, Satoshi Ishihara, Shinichi Nakayama
Thorax
Impact of COVID-19 lockdown on emergency asthma admissions and deaths: national interrupted time series analyses for Scotland and Wales
Gwyneth A Davies, Mohammad A Alsallakh, Shanya Sivakumaran, Eleftheria Vasileiou, Ronan A Lyons, Chris Robertson, Aziz Sheikh, EAVE II Collaborators
American Journal of Emergency Medicine
A coronavirus disease 2019 (COVID-19) patient with bilateral orchitis
Rachel E Bridwell, Daniel R Merrill, Sean A Griffith, Jesse Wray, Joshua J Oliver
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PeerVoice invites you to explore the education and resources on this site that provides a comprehensive approach to managing your patients.

User-friendly learning modules available in short and accessible formats.


Insights and developments from leading experts.


Continuously updated news and conference coverage.


Helpful resources for your practice and patients.


Resource Library

CRRT Online: Acute Therapy Resources

Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group

Nadim MK et al. J Am Heart Assoc. 2018;7:e008834

KDIGO Clinical Practice Guideline for Acute Kidney Injury

Kidney Int Suppl. 2012;2:1-128

Fluid Management for the Prevention and Attenuation of Acute Kidney Injury

Prowle JR et al. Nat Rev Nephrol. 2014;10:37-47

Fluid Management in Acute Kidney Injury

Goldstein SL. J Intensive Care Med. 2014;29:183-189

Indications and Management of Mechanical Fluid Removal in Critical Illness

Rosner MH et al. Br J Anaesth. 2014;113:764-771

Recovery After Acute Kidney Injury

Kellum JA et al. Am J Respir Crit Care Med. 2017;195:784-791

Prevention of Cardiac Surgery–Associated AKI by Implementing the KDIGO Guidelines in High-Risk Patients Identified by Biomarkers: The PrevAKI Randomised Controlled Trial

Meersch M et al. Intensive Care Med. 2017;43:1551-1561

Effect of Remote Ischaemic Preconditioning on Kidney Injury Among High-Risk Patients Undergoing Cardiac Surgery: A Randomised Clinical Trial

Zarbock A et al. JAMA. 2015;313:2133-2141

Strategies for the Optimal Timing to Start Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury

Bagshaw SM, Wald R. Kidney Int. 2017;91:1022-1032

Early vs Late Initiation of Renal Replacement Therapy Impacts Mortality in Patients With Acute Kidney Injury Post-Cardiac Surgery: A Meta-Analysis

Zou H et al. Crit Care. 2017;21:150