Managing Organ Dysfunction in the ICU

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Predicting Risk of Persistent Severe Acute Kidney Injury: The Role of CCL14

John A. Kellum, MD, MCCM
11 November 2020

Exploring the Implications of Early Biomarkers for Persistent Severe AKI

Claudio Ronco, MD
11 November 2020

Hypercapnia in the Intensive Care Unit: What Do I Need to Know?

Eddy Fan, MD, PhD
8 May 2019

The Role of Extracorporeal Carbon Dioxide Removal (ECCO₂R) in Patients With Acute Respiratory Distress Syndrome (ARDS)

Alain Combes, MD, PhD
8 May 2019

Acute Kidney Injury: A Significant Complication After Cardiac Surgery

John A. Kellum Jr., MD, MCCM
15 March 2019

Best Practices and Preferred Approaches to Managing CSA-AKI in the ICU

Alexander Zarbock, MD
15 March 2019

The Importance of Managing Fluid Overload in Acute Kidney Injury

Stuart L. Goldstein, MD, FAAP, FASN, FNKF
26 April 2018

Managing Fluid Overload in AKI: Best Practices and Preferred Approaches to RRT

John R. Prowle, MA, MB, BChir, MSc, MD, FFICM, FRCP
26 April 2018

Patient Case Studies

50-year-old Asian male presented to the emergency department with sudden onset of bilateral lower limb weakness preceded...

16-year-old female complaining of progressive dyspnea and chest pain over the course of one to two months with radiographic...

24-year-old female patient with a past medical history of tuberous sclerosis, gestational hypertension, stable renal angiomyolipoma,...

36-year-old woman, secundigravida and nulliparous, was admitted to the emergency obstetric unit with acute pelvic pain. The...

46-year old African American woman who presented to the emergency department with one week of progressive bilateral deafness...

In the News

Infectiousness Peaks Early in Patients With COVID-19, Emphasising the Need to Rapidly Isolate Cases

A systematic review and meta-analysis of 3 human coronaviruses, published in The Lancet Microbe, suggests that people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are most likely to be highly infectious in the first week after symptom onset, highlighting the need to...

High Prevalence of SARS-CoV-2 Genetic Variation, D614G Mutation in Children With COVID-19

By Denise Baez NEW YORK -- November 20, 2020 -- A whole genome study in children with coronavirus disease 2019 (COVID-19), published in Open Forum Infectious Diseases, has found a greater than expected genetic diversity across the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome...

Study Suggests a Potential Link Between SARS-CoV-2 Mutations, Disease Severity in Children

When it comes to children, it is becoming clear that coronavirus disease 2019 (COVID-19) impacts them more than was initially thought, and a study published in Open Forum Infectious Diseases has, for the first time, found a possible link between specific viral mutations and severity of the disease...

Delirium Can Signal Presence of COVID-19 in Asymptomatic Older Patients

A study published in JAMA Network Open supports evidence that older persons admitted to emergency departments (ED), and subsequently test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), often present with delirium when they show no other typical coronavirus disease 2019 (...

FDA Authorises Baricitinib, Remdesivir Combo for Hospitalised Patients With COVID-19

The US Food and Drug Administration issued an emergency use authorisation (EUA) for baricitinib, in combination with remdesivir, for the treatment of suspected or laboratory confirmed coronavirus disease 2019 (COVID-19) in hospitalised adults and paediatric patients aged 2 years and older requiring...

Conference Reports

D-Dimer Levels Alone Not Enough to Initiate Anticoagulation in Hospitalised Patients With COVID-19

By Eric Ramos

CHICAGO -- November 19, 2020 -- Deep venous thrombosis (DVT) was frequently diagnosed in patients hospitalised with coronavirus disease 2019 (COVID-19) who underwent imaging due to elevated D-Dimer levels; however, there was considerable overlap of peak D-Dimer values
...

Majority of Patients With Asthma Do Not Receive Guideline-Directed Therapy in the Emergency Department

By Ed Susman

WEST PALM BEACH, Fla -- November 19, 2020 -- When patients who are experiencing asthma exacerbation present at the emergency department, they frequently do not receive guideline-directed treatment, education, or medication, according to a study presented at the Virtual 2020...

Risk of COVID-19 Infection Not Higher in Patients With Cancer Receiving Immunotherapy

By Eric Ramos

CHICAGO -- November 10, 2020 -- Treatment with immune checkpoint inhibitors does not appear to be a risk factor for contracting coronavirus disease 2019 (COVID-19), according to a study presented at the Virtual 35th Annual Meeting of the Society of Immunotherapy of Cancer (...

Adding Dantrolene Sodium Suspension to Body Cooling Improves Outcomes in Patients With Exertional Heat Stroke

By Louise Gagnon

OTTAWA, Ontario -- November 3, 2020 -- The adjunctive use of dantrolene sodium suspension to treat exertional heat stroke, in addition to body cooling, improved recovery of loss of consciousness, according to research presented at the 2020 Virtual Meeting of the American...

NSAID Use Not Linked to Increased Risk of Severe COVID-19

By Louise Gagnon

OTTAWA, Ontario -- November 3, 2020 -- Use of non-steroidal anti-inflammatory drugs (NSAIDs) does not appear to significantly increase the risk of critical coronavirus disease 2019 (COVID-19) illness, according to a study presented at the 2020 Virtual Meeting of the...

Recently Published

Abstracts in Multiple Sclerosis

American Journal of Roentgenology

Trends in Use of Diagnostic Imaging for Abdominal Pain in U.S. Emergency Departments

Ralph C Wang, Aaron E Kornblith, Jacqueline Grupp-Phelan, Rebecca Smith-Bindman, Lillian S Kao, Jahan Fahimi

JAMA Cardiology

Effect of a Self-care Intervention on 90-Day Outcomes in Patients With Acute Heart Failure Discharged From the Emergency Department: A Randomized Clinical Trial

Sean P Collins, Dandan Liu, Cathy A Jenkins, Alan B Storrow, Phillip D Levy, Peter S Pang, Anna Marie Chang, Douglas Char, Deborah J Diercks, Gregory J Fermann, Jin H Han, Brian Hiestand, Christopher Hogan, Christina J Kampe, Yosef Khan, Sangil Lee, JoAnn Lindenfeld, Jennifer Martindale, Candace D McNaughton, Karen F Miller, Carolyn Miller-Reilly, Kelly Moser, W Frank Peacock, Chad Robichaux, Russell Rothman, Jon Schrock, Wesley H Self, Adam J Singer, Sarah A Sterling, Michael J Ward, Cheryl Walsh, Javed Butler

Journal of the American Medical Association (JAMA)

Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial

Suzanne Schuh, Judy Sweeney, Maggie Rumantir, Allan L Coates, Andrew R Willan, Derek Stephens, Eshetu G Atenafu, Yaron Finkelstein, Graham Thompson, Roger Zemek, Amy C Plint, Jocelyn Gravel, Francine M Ducharme, David W Johnson, Karen Black, Sarah Curtis, Darcy Beer, Terry P Klassen, Darcy Nicksy, Stephen B Freedman, Pediatric Emergency Research Canada (PERC) Network

Zeitschrift fur Gastroenterologie

[Management of hemostasis in gastroenterology critical care]

Marcus M Mücke, Wolfgang Miesbach, Kai-Henrik Peiffer, Victoria T Mücke, Jörg Bojunga

Pediatric Emergency Care

Respiratory Pathogen Detection in Pediatric Patients Intubated for Presumed Infection

Nathan Jamieson, Manzilat Akande, Todd Karsies, Rachel M Smith, David Kline, Sandra P Spencer

Full-Text Articles

BMC Emergency Medicine

Validation of age-specific survival prediction in pediatric patients with blunt trauma using trauma and injury severity score methodology: a ten-year Nationwide observational study

Chiaki Toida, Takashi Muguruma, Masayasu Gakumazawa, Mafumi Shinohara, Takeru Abe, Ichiro Takeuchi, Naoto Morimura

Internal and Emergency Medicine

Clinical characteristics and respiratory support of 310 COVID-19 patients, diagnosed at the emergency room: a single-center retrospective study

Sandro Luigi Di Domenico, Daniele Coen, Marta Bergamaschi, Valentina Albertini, Leonardo Ghezzi, Michela Maria Cazzaniga, Valeria Tombini, Riccardo Colombo, Nicolò Capsoni, Tommaso Coen, Katia Barbara Cazzola, Marina Di Fiore, Laura Angaroni, Marco Alberto Strozzi

PLoS Medicine

Diagnostic performance of congestion score index evaluated from chest radiography for acute heart failure in the emergency department: A retrospective analysis from the PARADISE cohort

Masatake Kobayashi, Amine Douair, Kevin Duarte, Déborah Jaeger, Gaetan Giacomin, Adrien Bassand, Victor Jeangeorges, Laure Abensur Vuillaume, Gregoire Preud'homme, Olivier Huttin, Faiez Zannad, Patrick Rossignol, Tahar Chouihed, Nicolas Girerd

Monaldi Archives for Chest Disease, Pulmonary Series

Diagnostic accuracy of inferior vena cava evaluation in the diagnosis of acute heart failure among dyspneic patients

Alfonso Sforza, Maria Viviana Carlino, Mario Guarino, Ilaria Fucile, Nicola De Luca, Costantino Mancusi

Radiologia Medica (Torino)

Chest CT in the emergency department for suspected COVID-19 pneumonia

Anna Palmisano, Giulia Maria Scotti, Davide Ippolito, Marco J Morelli, Davide Vignale, Davide Gandola, Sandro Sironi, Francesco De Cobelli, Luca Ferrante, Marzia Spessot, Giovanni Tonon, Carlo Tacchetti, Antonio Esposito